Allied Psychiatry and Mental Health provides Spravato® nasal ketamine to patients in Newport Beach and Orange County, CA who are seeking support for treatment-resistant mental health conditions. This FDA-approved nasal spray is designed for individuals who have not experienced adequate results with traditional oral antidepressants. Under the supervision of double board-certified, Harvard-trained psychiatrist Hadi Estakhri, MD, treatment is administered in a safe, controlled clinical setting.

Spravato® is an FDA-approved esketamine nasal spray designed for adults with treatment-resistant depression. Unlike traditional medications that target the monoamine system, this therapy acts on the glutamate system, which plays a role in brain signaling pathways. Treatment is administered under clinical supervision and is typically used alongside an oral antidepressant as part of a comprehensive care plan.

Before beginning treatment, Hadi Estakhri, MD, conducts a comprehensive psychiatric evaluation to determine whether Spravato® is appropriate for your needs. This assessment considers your medical history, current symptoms, and prior medication use to help guide a personalized treatment approach.

You will self-administer the nasal spray under the direct supervision of trained medical staff in a private, comfortable treatment room. Your response will be observed throughout the session to support safe and proper administration.

After administration, you will remain in the office for approximately two hours for monitoring. This observation period allows the care team to assess your condition and provide support as needed before you leave the facility.

Because the medication may cause temporary drowsiness or changes in perception, you will need to arrange for a friend or family member to drive you home. Patients are generally advised to rest and avoid driving or operating machinery until the following day.
Spravato® (esketamine) works differently from traditional antidepressants by acting on the glutamate system, which is involved in brain signaling pathways. This alternative approach may be considered for individuals who have not experienced adequate results with standard treatments.
Treatment is administered in a controlled clinical setting under the supervision of trained medical professionals. This structured environment allows for proper monitoring during each session and supports safe, guided care.
The nasal spray format offers a non-invasive alternative to intravenous therapies. It is designed for in-office use, allowing patients to receive treatment in a comfortable and streamlined setting.
Spravato® is typically used as part of a broader treatment plan that may include oral antidepressants and ongoing clinical evaluation. Following the recommended schedule helps support continuity of care and long-term management.
The cost of Spravato® in Newport Beach & Orange County, CA, may vary depending on factors such as insurance coverage, pharmacy pricing, and your individualized treatment plan. In many cases, patients can expect a range of approximately $300–$900 per session. Our team can assist you in understanding your benefits and estimating potential out-of-pocket expenses. Contact us to learn more or request personalized cost information.
Our office is on Dove Street next to John Wayne Airport, so most of Orange County is a short drive away. Pick your city to see the drive and what a course of Spravato looks like from there.
Allied Psychiatry and Mental Health
1401 Dove St, Suite 420, Newport Beach, CA 92660
Monday to Friday, 9:00 am to 5:00 pm · 949-945-0927

Hadi Estakhri, MD, is a Harvard-trained, board-certified psychiatrist with extensive experience in interventional psychiatry. Patients receive care in a private, supportive environment where safety and clinical excellence are the primary focus. Allied Psychiatry and Mental Health prioritizes individualized treatment plans to ensure every person receives the specific support necessary for their recovery journey.
At our office, Spravato usually comes to about $300 to $900 per session, depending on your insurance and pharmacy pricing. Many commercial plans cover it, and the manufacturer runs a savings program that can lower copays for eligible patients.
You need a psychiatric evaluation confirming depression that has not improved after at least two antidepressants, taken at a proper dose for long enough. Most insurers also want prior authorization, which our team handles for you.
No. By FDA rules Spravato is only given in a certified office. You use the spray under supervision, stay at least two hours while we monitor you, and should not drive until the next day after a full night of sleep.
Spravato is not used in people with an aneurysm or abnormal blood vessels in the brain, the chest or the limbs, a history of bleeding in the brain, or an allergy to esketamine or ketamine. High blood pressure and pregnancy need a careful talk first, and your blood pressure is checked before and after each dose.
The first four weeks have two sessions a week. Weeks five to eight drop to one a week. After that, most people continue weekly or every two weeks for as long as the benefit lasts, and Dr. Estakhri reviews the schedule with you.
Not quite. Spravato is esketamine, one form of the ketamine molecule, made as an FDA-approved nasal spray for depression. IV ketamine is given as an infusion and used off-label. Read more in our Spravato vs. ketamine article.
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